Chapter 5: Microbial bioprocessing of health promoting food supplements (2021)

For centuries, human beings have utilized microorganism for their abilities to produce various bioactive compounds/metabolites of interest, such as food supplements or food ingredients. The food supplements include a vast array of products, i.e., vitamins, minerals, amino acids, polyunsaturated fatty acids (PUFAs), antioxidants (polyphenols, carotenoids), amino acids/peptides and their derivatives, etc., that are synthesized from microorganisms for providing health and nutrition to consumers. The data available from different sources like genomic, transcriptomic, proteomic, and metabolomic studies have provided ways to engineer microorganisms for development of food supplements of commercial importance. Synthetic biology/metabolic engineering envisages the use of genetic parts/ tools [promoter, transcription factors, ribosomal binding sites (RBS), degradation tags, and transcriptional terminators] in microbial system for synthesis of biocommodities including food supplements. Microbial synthesis is an alternative to chemical methods for production of food supplements and uses organic feedstocks. This chapter focuses on the classification and types of food supplements, various industrially important organisms involved, bioprocessing route, market trend, and regulatory issues

chap5 Microbial bioprocessing of health promoting food supplements.pdf